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William Hayes

Director, Library & Literature Informatics at Biogen Idec

Cambridge, MA United States

What I Do:

Manage Library & Literature Informatics Group and work on strategic initiatives regarding Knowledge Discovery, information access, analysis and management.

Expertise:

Experience:

Biogen Idec

Director, Library & Literature Informatics

Jan 2005 - Current

Develop enhanced Knowledge Discovery and Delivery capabilities for Biogen Idec.

Manage the Library and Literature Informatics Group. Develop and deploy information management, collaborative technologies. Develop and deploy text analytics. Automate library operations and improve services.

AstraZeneca

Head of Cross-Discovery Strategic Informatics

Mar 2002 - Dec 2004

Managed projects and strategy in Research Informatics broader than the disciplines of Cheminformatics, Bioinformatics, etc. Focused efforts on text, data and image mining. Cross-functional database development.

GlaxoSmithKline

Bioinformatics Research Scientist

Jun 1998 - Feb 2002

Human Genome analysis projects focusing on internal Gene Catalog and genome-wide promoter analyses. Developed expertise in desktop grid computing for additional compute cycles for genome-wide analyses.

Education:

Georgia Institute of Technology

PhD, Molecular Biology

1993 - 1998

Thesis: "Pattern recognition and signal detection in gene finding". Doctoral work: Bioinformatics, bacterial gene prediction, molecular biology

Georgia Institute of Technology

Bachelor's, Aerospace Engineering

1984 - 1987

Publications:

Books:

in silico Technology in Drug Target Identification and Validation; Chapter ?

2006

in silico Technology in Drug Target Identification and Validation; Chapter ?

2006

Semantic Web: Revolutionizing Knowledge Discovery in the Life Sciences; Chapter 3

2007

in silico Technology in Drug Target Identification and Validation; Chapter X

2006

Speaking Engagements:

Enterprise 2.0 Conference

AIM for bioPharma

Alert Information Management (AIM) is about delivering dynamic information where and when it is needed. With a variety of ever changing information feeds (email alerts, updated web pages, RSS feeds, internal company news, intranet portal, etc), we need to manage these feeds to optimize their value and not get overloaded. RSS/Atom was selected as the common protocol for these information streams. Discussed will be the overall strategy, specific use cases and resulting advantages of using the Newsgator Enterprise Server with auxiliary synchronized news readers/output news channels. Also presented will be the required corporate environmental changes and attendant applications that need to be put in place to take better advantage of this approach to managing continuous information streams.

Jun 2008

Enterprise 2.0 Conference

AIM for bioPharma

Alert Information Management (AIM) is about delivering dynamic information where and when it is needed. With a variety of ever changing information feeds (email alerts, updated web pages, RSS feeds, internal company news, intranet portal, etc), we need to manage these feeds to optimize their value and not get overloaded. RSS/Atom was selected as the common protocol for these information streams. Discussed will be the overall strategy, specific use cases and resulting advantages of using the Newsgator Enterprise Server with auxiliary synchronized news readers/output news channels. Also presented will be the required corporate environmental changes and attendant applications that need to be put in place to take better advantage of this approach to managing continuous information streams.

Jun 2008

Enterprise 2.0 Conference

AIM for bioPharma

Alert Information Management (AIM) is about delivering dynamic information where and when it is needed. With a variety of ever changing information feeds (email alerts, updated web pages, RSS feeds, internal company news, intranet portal, etc), we need to manage these feeds to optimize their value and not get overloaded. RSS/Atom was selected as the common protocol for these information streams. Discussed will be the overall strategy, specific use cases and resulting advantages of using the Newsgator Enterprise Server with auxiliary synchronized news readers/output news channels. Also presented will be the required corporate environmental changes and attendant applications that need to be put in place to take better advantage of this approach to managing continuous information streams.

Jun 2008

C-SHALS

Competitive Intelligence Mashups using Semantic Web Technology

There are many drug pipeline and clinical trial databases available none of which are complete or provide a comprehensive set of meta-data. In order to make effective decisions on product development and positioning, we need to be able to understand what competitors have in the pipeline and continually compare it with Biogen Idec's pipeline. The pilot project we initiated to provide a highly customized view of the Rheumatology drug pipeline was made possible and easy to replicate for other therapeutic areas only after bringing the Simile Exhibit and Timeline technology into the project. Competitive intelligence projects are almost always highly targeted requiring a great deal of customization. These projects require significant data integration and excellent visualization capabilities. Utilizing semantic web technology makes the presentation and re-distribution of highly-targeted drug pipeline data tractable.

Mar 2008

C-SHALS

Competitive Intelligence Mashups using Semantic Web Technology

There are many drug pipeline and clinical trial databases available none of which are complete or provide a comprehensive set of meta-data. In order to make effective decisions on product development and positioning, we need to be able to understand what competitors have in the pipeline and continually compare it with Biogen Idec's pipeline. The pilot project we initiated to provide a highly customized view of the Rheumatology drug pipeline was made possible and easy to replicate for other therapeutic areas only after bringing the Simile Exhibit and Timeline technology into the project. Competitive intelligence projects are almost always highly targeted requiring a great deal of customization. These projects require significant data integration and excellent visualization capabilities. Utilizing semantic web technology makes the presentation and re-distribution of highly-targeted drug pipeline data tractable.

Mar 2008

C-SHALS

Competitive Intelligence Mashups using Semantic Web Technology

There are many drug pipeline and clinical trial databases available none of which are complete or provide a comprehensive set of meta-data. In order to make effective decisions on product development and positioning, we need to be able to understand what competitors have in the pipeline and continually compare it with Biogen Idec's pipeline. The pilot project we initiated to provide a highly customized view of the Rheumatology drug pipeline was made possible and easy to replicate for other therapeutic areas only after bringing the Simile Exhibit and Timeline technology into the project. Competitive intelligence projects are almost always highly targeted requiring a great deal of customization. These projects require significant data integration and excellent visualization capabilities. Utilizing semantic web technology makes the presentation and re-distribution of highly-targeted drug pipeline data tractable.

Mar 2008

Scottish Bioinformatics Forum - Biomedical Text Mining

Text Mining and Information Needs of bioPharma

Information needs and production capabilities of text analytics and infrastructure drive the utility of text analytics technologies in bioPharma as in every industry. It takes a great deal of basic infrastructure to deal with large document collections that continue to grow, continuously evolving ontologies, and continous information streams (news articles, etc). Beyond basic management of the raw material, one needs text analytics technologies that fit into a framework to allow for integration. Further, the results of text mining are non-trivial to manage as regards information delivery that is collaborative, re-usable and integratable. This presentation will discuss the challenges and some of the successes found in bioPharma as one example of a customer of text mining in the biomedical community.

Feb 2008

Elsevier Corporate Event - London, UK

A view from the bleeding edge of text mining

An overview of the latest capabilities either in production or ready to go into production for large-scale information discovery and delivery for corporate needs.

Dec 2007

Elsevier Corporate Event - London, UK

A view from the bleeding edge of text mining

An overview of the latest capabilities either in production or ready to go into production for large-scale information discovery and delivery for corporate needs.

Dec 2007

BioIT World

Literature Informatics: Leveraging External Knowledge for Drug Discovery

This presentation will demonstrate how to provide comprehensive analyses of the literature and related databases for biomarker development, toxicology and protein target validation. Literature informatics not only provides more comprehensive extraction of information and facts from the literature than is available manually, it also permits quantitative and qualitative assessments of the resulting information. Visualizing data extracted from the literature in graphs or diagrams can highlight valuable information that is not necessarily obvious from a tabular view of the raw data. Social and technological changes are needed to deploy literature informatics and commitments are required from several departments during deployment (Informatics, IT and most importantly the Research Library).

Apr 2007

BioIT World

Literature Informatics: Leveraging External Knowledge for Drug Discovery

This presentation will demonstrate how to provide comprehensive analyses of the literature and related databases for biomarker development, toxicology and protein target validation. Literature informatics not only provides more comprehensive extraction of information and facts from the literature than is available manually, it also permits quantitative and qualitative assessments of the resulting information. Visualizing data extracted from the literature in graphs or diagrams can highlight valuable information that is not necessarily obvious from a tabular view of the raw data. Social and technological changes are needed to deploy literature informatics and commitments are required from several departments during deployment (Informatics, IT and most importantly the Research Library).

Apr 2007

BioIT World

Literature Informatics: Leveraging External Knowledge for Drug Discovery

This presentation will demonstrate how to provide comprehensive analyses of the literature and related databases for biomarker development, toxicology and protein target validation. Literature informatics not only provides more comprehensive extraction of information and facts from the literature than is available manually, it also permits quantitative and qualitative assessments of the resulting information. Visualizing data extracted from the literature in graphs or diagrams can highlight valuable information that is not necessarily obvious from a tabular view of the raw data. Social and technological changes are needed to deploy literature informatics and commitments are required from several departments during deployment (Informatics, IT and most importantly the Research Library).

Apr 2007

SLA Pharma

Drug Discovery Process and the Information Professionals Role

Review of how advanced technologies can be used to more effectively deliver information to Library customers in bioPharma.

Mar 2007

SLA Pharma

Drug Discovery Process and the Information Professionals Role

Review of how advanced technologies can be used to more effectively deliver information to Library customers in bioPharma.

Mar 2007

EIM Conference

Semantic Search And Its Role In Finding Information

The potential of the Semantic Web to transform knowledge management is enormous but still on the horizon. Semantic Search technologies, however, are already being deployed into corporations as production capabilities. This presentation will review the advantages gained by semantic search technologies based upon real world experience in delivering information using Agile NLP (as an example of Semantic Search technology). The presentation will also provide a review of the variety of solutions and suggestions on uses.

Jan 2007

EIM Conference

Semantic Search And Its Role In Finding Information

The potential of the Semantic Web to transform knowledge management is enormous but still on the horizon. Semantic Search technologies, however, are already being deployed into corporations as production capabilities. This presentation will review the advantages gained by semantic search technologies based upon real world experience in delivering information using Agile NLP (as an example of Semantic Search technology). The presentation will also provide a review of the variety of solutions and suggestions on uses.

Jan 2007

EIM Conference

Semantic Search And Its Role In Finding Information

The potential of the Semantic Web to transform knowledge management is enormous but still on the horizon. Semantic Search technologies, however, are already being deployed into corporations as production capabilities. This presentation will review the advantages gained by semantic search technologies based upon real world experience in delivering information using Agile NLP (as an example of Semantic Search technology). The presentation will also provide a review of the variety of solutions and suggestions on uses.

Jan 2007

KM World

Improving Information Flows

Automating the assembly and distribution of important company, product, industry, and competitive information throughout the enterprise is revolutionized with RSS. Hear how Biogen Idec, a Fortune 1000 company with market-leading drugs for treating a number of illnesses, has used RSS to get high-value business information into the hands of employees.

Jan 2007

Linguamatics User Conference

Overview of workflow technology and how it can be used with I2E.

Jan 2007
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